What’s already known about this topic?
Overt hypothyroidism has been associated with increased fatal and
nonfatal cardiovascular disease. However, studies of the association of
subclinical hypothyroidism and cardiovascular risk have shown
controversial results, particularly in mild subclinical hypothyroidism
(thyrotropin [TSH] <10 µIU/ml).
In terms of cardiovascular risk prediction, carotid intima-media
thickness is a marker of atherosclerosis well studied.