Conclusion
Disseminated cryptococcosis was attributed to the final cause of death in the deceased with underlying HIV disease, who was not diagnosed with either of these conditions during her lifetime. Clinical autopsy should be conducted meticulously along with adequate ancillary tests to correctly identify the cause of death as it can provide valuable information about disease burden in the region. Minimal invasive tissue sampling technique can be a useful tool in determining cause of death in low resource settings. In mortality cases with likely infectious conditions and other natural diseases, clinical autopsies have an important clinical and public health implications.