Final PFTs
The median duration of follow-up was 29 months (range: 6-80 months). At the final PFTs, the median values for FEV1, FVC, FEV1/FVC ratio and MMEF25%–75% were 57.8%, 76.1%, 77.85% and 26.2% respectively (Table 2), while the children with positive results for bronchodilator responses were 7 (58.3%) (data was not given). The improvements were also significant when the mean percent variation from the previous measurement was calculated (increases of 15.89% and 24.65% for FEV1and MMEF25-75%, respectively). The improved percentage was not as high as that in the baseline PFTs. And the mean absolute volume change was 0.16 L for FEV1 and 0.18L/s for MMEF25%-75% (Table 3).