Participants
Twelve children were included during the study period, and data were
obtained from clinical records. The average age at diagnosis was 36
months. All patients were diagnosed with PIBO according to a history of
severe lower respiratory infection or acute lung injury in previously
healthy subjects; exercise intolerance, recurrent or persistent
wheezing, coughing and tachypnea with extensive wheezing and moist
crackles in lungs lasting for more than 6 weeks; severe obstructive lung
disease on PFTs; characteristic changes of mosaic perfusion pattern,
bronchial wall thickening, bronchial dilation and vascular attenuation
on chest HRCT[6]; bronchopulmonary dysplasia,
cystic fibrosis (CF), pulmonary tuberculosis, immunodeficiency and
congenital heart disease were excluded on the basis of clinical,
radiological and laboratory data. We followed their PFT results since
they were able to perform the spirometry maneuver until November 2019.
The average time was 29 months (range of 6-80months) for follow-up of
PFTs.