Time undetectable
Within both cohorts, there was no statistical difference in time undetectable, defined as time for which tobramycin serum concentration was <0.5 mg/L, between patient encounters in which FEV1 returned to baseline, versus did not return to baseline, with median time undetectable of 9 and 8 hours, respectively (p=0.333). When comparing overall incidence of AKI, there was no difference in median time undetectable, with a median of 8 hours in encounters where the patient did and did not develop AKI.