Time undetectable
Within both cohorts, there was no statistical difference in time
undetectable, defined as time for which tobramycin serum concentration
was <0.5 mg/L, between patient encounters in which
FEV1 returned to baseline, versus did not return to
baseline, with median time undetectable of 9 and 8 hours, respectively
(p=0.333). When comparing overall incidence of AKI, there was no
difference in median time undetectable, with a median of 8 hours in
encounters where the patient did and did not develop AKI.