Factors affecting complete clinical success – results of logistic regression analysis
In univariate logistic regression analysis the factors that reduced the probability of clinical success were as follows: all types of fibrous tissue binding sites: decrease of 88.7% (OR=0.113; p<0.001), fibrous tissue binding the lead to the SVC: decrease of 85.6% (OR=0.144; p<0.001), to the RA: decrease of 83.1% (OR= 0.169; p< 0.001), to the TV: decrease of 80.7% (OR= 0.153; p<0.001), to the RV: decrease of 80.7% (OR= 0.193; p<0.001), lead-to-lead binding sites: decrease of 83.2% (OR= 0.168; p< 0.001) and the presence of AMEL: decrease of 76.4% (OR=0.236; p< 0.01), including the presence of fibrous tissue encasing the lead: decrease of 63.7% (OR=0.363; p<0.05) and lead thickening: decrease of 81.2% (OR=0.188; p<0.001).
Multivariate analysis showed that fibrous tissue binding the lead to the TV (OR=0.307; p<0.05) was the strongest predictor of clinical success. Lead-to-lead binding sites (OR= 0,378; p= 0,054) and lead thickening (OR= 0.385; p=0.059) approached the borderline of significance (Table 4).