Factors influencing the occurrence of major complications – results of logistic regression analysis
Univariate logistic regression analysis showed that the factors increasing the probability of major complications were: all types of fibrous tissue binding sites: 10-fold increase (OR=9.989; p<0.001), fibrous tissue binding the lead to the SVC: 8-fold increase (OR=7.972; p<0.001), to the RA: nearly 7-fold increase (OR= 6.762; p< 0.001), to the TV: 6-fold increase (OR= 6.169; p<0.001), to the RV: 6-fold increase (OR= 6.045; p<0.001), lead-to-lead binding sites: 7.5-fold increase (OR= 7.441; p< 0.001) and the presence of AMEL: 5-fold increase (OR=5.009; p< 0.01), and especially fibrous tissue encasing the lead: 3-fold increase (OR=2.971; p<0.05) and lead thickening: 5-fold increase (OR=4.958; p<0.001).
Multivariate analysis showed that lead-to-lead binding sites were the strongest predictor of major complications (3-fold increase; OR=3.034; p<0.05). Fibrous tissue binding the lead to the RA: 2.5-fold increase (OR=2.534; p=0.089) and to the TV: 2.5-fold increase (OR= 2.570; p= 0.085) approached the borderline of significance (Table 3).