Statistical analysis
Continuous data are reported as mean ± standard deviation or median
(interquartile range [IQR]) depending on their distribution.
Categorical data are presented as frequencies (percentages). Comparative
analyses involved the Wilcoxon matched-pairs signed rank test. Complete
data were available for all patients. Statistical analyses were
performed with JMP v9 (SAS Institute Inc., Cary, NC) and PRISM v7
(GraphPad, San Diego, CA).