Figure Legends

Figure 1. Cell growth of suspension adapted Vero cells in IHM03 (A) and MDXK (B) medium in a 1 L bioreactor in batch mode. The concentration of the main metabolic substrates (glucose, L-glutamine) and by-products (lactate, ammonia) are given in mM.
Figure 2. rVSV-ZEBOV infection of suspension adapted Vero cells at different MOIs ranging from 0.001 to 0.1 in 125 mL shake flask in IHM03 medium at a cell density of 1 × 106 cells/mL. Infectious viral titers expressed as TCID50/mL are plotted against the time post-infection. Bars represent the mean of the three independent samples ± standard deviation.
Figure 3. rVSV-ZEBOV infection of suspension adapted Vero cells at different cell densities ranging from 1 × 106 to 4 × 106 cells/mL in 125 mL shake flask in IHM03 medium. Infectious viral titers expressed as TCID50/mL are plotted against the time post-infection. Bars represent the mean of the three independent samples ± standard deviation.
Figure 4. rVSV-ZEBOV (A), rVSV-HIV (B) and rVSVInd-msp -SF-Gtc (C) infections of suspension adapted Vero cells cultivated in either IHM03 or MDXK medium at an MOI of 0.01, in 125 mL shake flask at a cell density of 1 × 106 cells/mL. Infectious viral titers expressed as TCID50/mL are plotted against the time post-infection. Bars represent the mean of the three independent samples ± standard deviation.
Figure 5. Comparison of the production of rVSV-ZEBOV in suspension adapted Vero cells cultivated in either IHM03 or MDXK medium in a 1 L bioreactor in batch mode. Infectious viral titers expressed as TCID50/mL and the number of viral genomes in VG/mL are plotted against the time post-infection.
Figure 6. Comparison of the production of rVSV-HIV in suspension adapted Vero cells cultivated in either IHM03 or MDXK medium in a 1 L bioreactor in batch mode. Infectious viral titers expressed as TCID50/mL and the number of viral genomes in VG/mL are plotted against the time post-infection.
Figure 7. Comparison of the production of rVSVInd-msp -SF-Gtc in suspension adapted Vero cells cultivated in either IHM03 or MDXK medium in a 1 L bioreactor in batch mode. Infectious viral titers expressed as TCID50/mL and the number of viral genomes in VG/mL are plotted against the time post-infection.