Variability of AMH
Several studies have reported that serum AMH levels are mildly decreased
in endometriomas than other ovarian tumors and severely declined as the
endometriosis is severe and bilateral19. Iwase et al
reported that decreased AMH levels were found after laparoscopic
excision of endometriomas and non-endometriotic cysts but the decrease
was more profound in endometriomas than in
non-endometriomas26. Hirokawa et al also reported that
the rate of decline of the serum AMH level was significantly higher in
the bilateral group than the unilateral group and was correlated with
the revised American Society for Reproductive Medicine( rASRM)
score22. Laparoscopic cystectomy further exerted a
significant negative impact on ovarian reserve measured by serum AMH
levels in both short and long term observations27.
Tsolakidis et al reported that the mean serum AMH level was
significantly reduced 6 months after surgery28. Chang
et al also observed a significant decrease in serum AMH levels 3 months
after laparoscopic cystectomy6.