Results
Initially the research strategy identified seventeen studies published
in the last 10 years. Thirteen articles were excluded on the basis of
failure to meet inclusion criteria. Finally the search revealed four
relative articles published between 2014 and 2019 and offered 336
patients for this analysis, 143 of which underwent SPL and 193 MPL
(Figure 1). Two of the studies were retrospective case-control studies,
one was randomized controlled trial and the other was non-randomized
concurrent control trial13-16. According to the
surgical outcomes none of the cases was converted to a different
surgical approach and no complication occurred during the perioperative
period. Serum AMH was similar between the two groups before the surgery
[MD=0.04, 95%CI (0.43, 0.52), p=0.8) and after the surgery
[MD=-0.15, 95%CI (0.53, 0.23), p=0.44]. Thus, the meta-analysis
demonstrated similar and non significant reduction in AMH levels between
the two groups four weeks after the procedure irrespective of the
surgical technique [MD=0.11, 95%CI (-0.01, 0.24), p=0.07] (Figure
2). Regarding analysis of hospital stay there was also no statistically
significant difference between two groups [MD=-0.26, 95%CI (-0.97,
0.45), p=0.48] (Figure 3). Perioperative outcomes analysis revealed
that operative time (min) was significantly longer [MD=0.57, 95%CI
(0.30, 0.83), p<0.00001] (Figure 4) and blood loss (ml) was
significantly higher [MD=0.58, 95%CI (0.04, 1.12) p=0.03] in SPL
group (Figure 5). The quality of these results is consistent but poor,
as illustrated by the number of the studies, substantial variation in
treatment effects and low precision of the point estimates.