1. INTRODUCTION
The new covid-19 coronavirus, a severe infectious disease with rapid
transmission to humans, was discovered in December 2019, and its
outbreak was declared by the World Health Organization as a public
health emergency and has now claimed the lives of millions worldwide1. Diagnosis of Covid - 19 disease is performed using
polymerase chain reaction tests, chest CT scans, and ELISA test kits2,3. Research published since 2019 claims that chest
CT scans, along with polymerase chain reaction tests and other
laboratory parameters, have the highest efficiency in detecting Covid 194,5. Therefore, chest CT scan and radiological reports
have been proposed as an adjunct to polymerase chain reaction tests as a
complementary method 6. No findings can completely
confirmed or rule out the possibility of COVID-19 7.
Some observational studies have been partially characterized Clinical,
laboratory, and imaging features of Covid-19, but until now few
systematic study on relate these features to each other have been
published to date 8. Laboratory tests scales in the
most patients with COVID-19 showed a significant changes in serum
pro-inflammatory cytokine levels and blood biochemical markers such as
interleukins, TNF-a, LDH, AST, ALT BUN, Creatinine, D-dimers, platelet
count, cardiac troponin, renal markers WBC, HB and Lymphocytes
(according to figure. 1) 9,10. Evaluation of clinical
features and radiological reports in severe cases of COVID-19 will help
in the initial prognosis, accurate diagnosis and treatment of patients
with Covid-19 11-13. It was detecting that there are
differences in the abundance of metabolic markers and biochemistry
indicators in COVID-19 patients than healthy, but there is a question
about the subject whether change in blood biochemistry markers are
associated with CT-scan findings and the severity of COVID-19 disease?
Most of the articles published in the field have reported the
epidemiological and clinical characteristics of patients with COVID-19
disease, but data regarding the relationship of laboratory
characteristics with CT-scan findings of infected individuals are
limited 14-16. However, the evaluation of lungs
involvement in CT scan and their relationship with laboratory indicator
including biochemical and hematological factors, is the best scale for
the severity and prognosis of Covid 19 patients 17.
Various studies described the epidemiological and clinical
characteristics of hospitalized patients 10,18-20.
However, there is a limited number of detailed analysis on blood
chemicals in discharged patients. In this study, we attempted that our
findings could be usable to development future clinical research
associated with COVID-19 infection. In concluded, this study aimed to
evaluate laboratory parameters and the relationship them with CT scan
reports and clinical outcomes in the diagnosis of patients with
COVID-19.