Results
Of the 68 patients allocated to the randomization, 34 were assigned to a placebo group. A total of 24 patients were lost at the 6-month follow-up and 8 additional patients were lost at the 12-month follow-up. In the control group 49 patients were enrolled, two patients were lost to follow-up (Fig. 1). All children were diagnosed with neoplastic diseases and had finished their cancer therapy at the time of removal of CVC. The patient demographics are summarized in Table I. No significant differences were found in the patient demographics between the groups.
Only two patients had non-Caucasian skin type; one patient with skin type 2 and one with skin type 5. The rest had skin type 1. The categorization was not made for the control group. Therefore, the skin type is not considered in the present study.