Conclusion
The results of the present study indicate that silicone gel sheet alone or in combination with application of glucocorticosteroid during sheet occlusion may improve scar outcome after removal of CVC in children treated for neoplastic diseases. Data assessed by the dermatologist showed significantly improved scar outcome for the intervention groups, however the result was not supported by the data assessed by the study nurse and the patients. The POSAS assessed by the patients and the study nurse showed no statistically significant difference between the intervention and control groups.
Overall, there is a need for larger studies and interventions that can distinguish between the effect of silicone gel sheet and the effect of glucocorticosteroid in combination with silicone gel sheet.