Study population
A retrospective observational study was conducted at a tertiary academic centre in Buenos Aires, Argentina. We included all consecutive cases of AS identified on our echocardiography database from August 2014 to January 2016. We included all patients that were at least 18 years old, had AS defined by a peak aortic jet velocity (Vpeak) >2m/s and were followed-up by the Structural Heart Disease Group. Patients with a previous intervention on the aortic or mitral valve or pregnant were excluded.
We collected clinical data including age, sex, height, weight, body surface area (BSA), systolic and diastolic blood pressures, heart rate, hypertension, dyslipidaemia, diabetes, coronary artery disease, medications, and history of smoking, metabolic syndrome,vascular disease and abdominal aortic aneurysm.