Statistical Analysis
Continuous variables were expressed as mean ± standard deviation or as median interquartile range (IQR), as appropriate and categorical variables were expressed as n (%). Continuous variables were tested for normality of distribution with a Shapiro–Wilk test and comparisons between BAV and TAV patients were done with two-tailed Student’s t test or a Fisher’s exact test, as appropriate.
Univariate analysis of all parameters obtained during patient recruitment was carried out to predict the primary and secondary endpoints. Then a multivariate analysis was performed and the criteria for introducing variables were their clinical relevance and statistical significance in the univariate analysis. Survival was computed using the Kaplan–Meier method and was compared between groups using the two-sample logrank test.
Statistical analysis was performed with STATA. A P-value <0.05 was considered significant.