Study design
The study protocol was approved by the ethics committee of the faculty of Medicine ,Cairo University .it was a prospective observational study on reverse remodeling in new onset heart failure patients with EF<40% . There is no universal imaging definition of reverse remodeling, but many studies have used statistically significant increases in LVEF or decreases in LV dimensions or volumes, while others have defined cut-offs for increases in LVEF (by 5–20 %) and/or decreases in LV dimensions or volumes (by 10–20 %) with a change ≥15 % often being considered significant