Study design
The study protocol was approved by the ethics committee of the faculty
of Medicine ,Cairo University .it was a prospective observational study
on reverse remodeling in new onset heart failure patients with
EF<40% . There is no universal imaging definition of reverse
remodeling, but many studies have used statistically significant
increases in LVEF or decreases in LV dimensions or volumes, while others
have defined cut-offs for increases in LVEF (by 5–20 %) and/or
decreases in LV dimensions or volumes (by 10–20 %) with a change ≥15
% often being considered significant