INTRODUCTION
The incidence of heart failure (HF) due to chemotherapy-induced
cardiomyopathy (CHIC) is increasing and is associated with poor clinical
outcomes. Conservative treatment with medications is often difficult,
especially in advanced HF 1 2.
Ivabradine, a specific If channel inhibitor, lowers the
sinus heart rate (HR) without affecting myocardial contractility. It is
indicated for controlling HR as a second-line medication after the
optimal beta-blocker therapy in patients with chronic HF and reduced
ejection fraction 3,4. However, some studies report
that ivabradine has a positive effect on the hemodynamics of
decompensated HF 5 67 8. Here, we report a case of
advanced HF related to CHIC refractory to conventional HF therapy
successfully treated with ivabradine.