MATERIALS AND METHODS
This retrospective study included a total of 1003 patients who underwent on-pump cardiac surgery in our institute between January 2016 and January 2020. The patients’ demographic characteristics, medical records, laboratory study findings, and clinical outcomes were retrospectively collected by searching the institutional clinical database. Surgical procedures included coronary artery bypass grafting (CABG), aortic valve replacement (AVR), mitral valve replacement (MVR), and combined procedures (Table1). Peripheral blood samples taken on the first day of hospitalization for all patients were noted. The whole blood cell count analysis were performed using Beckmann Coulter LH780 Hematology Analyzer device and Biochemical measurements were performed using Roche diagnostic Cobas 8000 (Manheim).
Other data, body mass index (BMI), preoperative left ventricular ejection fraction (LVEF), cross clamp (X-clamp) time, cardiopulmonary bypass (CPB) time, intraaortic balloon pump (IABP) usage, intensive care unit (ICU) stays, postoperative hospital-acquired infection and stroke were noted. We defined six types of infections after cardiac surgery as hospital-acquired infections Based on O’Keefe et al.15. These included urinary tract infection, pneumonia, harvest site infections, superficial sternal wound infection, deep sternal wound infection, and sepsis. We also noted that stroke events after surgery. The most commonly used definitions were stroke observed ’on waking’ or ’after extubation’ for early stroke after a symptom-free interval for delayed stroke. We used both to describe postoperative stroke.
The preoperative nutritional status of the patients was assessed using the PNI classification. PNI was calculated according to the formula: 10 x serum Albumin + 0.005 x total lymphocyte count (as previously described)13.
The study protocol was approved by the Bursa Yuksek Ihtisas Training and Research Hospital Ethics Committee (2011-KAEK-25 2020/03-11). The informed consent requirement was renounced due to the retrospective nature of the study.