Results:
175 patients (age 81.2±8.2 years, 61.2% male) with severe mitral
regurgitation (MR) were included. We divided our cohort into two groups
with a threshold of intraprocedural MG of 4.5 mmHg, which was determined
by the multivariate analysis for the prediction of 12-month mortality
(<4.5 mmHg: Group 1, ≥4.5 mmHg: Group 2).
Intraprocedural MG ≥4.5 mmHg was found to be the strongest independent
predictor for 12-month mortality (HR: 2.33, p=0.03, OR: 1.70, p=0.05)
and ≥3.9 mmHg was associated with adverse functional outcomes (OR: 1.96,
p=0.04).
The baseline leaflet-to-annulus index (>1.1) was found to
be the strongest independent predictor (OR: 9.74, p=0.001) for
unfavourable intraprocedural MG, followed by the number of implanted
clips (p=0.01), MG at baseline (p=0.02) and central clip implantation
(p=0.05).