Conclusion:
The present study can be accepted as a preliminary report on metabolomic alterations in BD patients with or without vascular involvement. As the etiopathogenesis of this chronic inflammatory disease is still not clearly known, our study can suggest some metabolomic indicators of disease prognosis. Especially for vascular involvement, finding a non-invasive molecule is of critical importance for both diagnosis and treatment of disease. As BD is accepteda as a vasculitis and endothelial dysfunction seems to be the pathognomonic signature of the disease, the early detection of candidate oxidative stress markers causing endothelial damage may bring early diagnosis and better clinical management.