*Corresponding email: Prima Hapsari Wulandari. Email:
primahapsari@outlook.com
ABSTRACT
Approximately 121.5 million individuals worldwide are
diagnosed with cardiovascular diseases. Advancing age increases the risk
of cardiovascular diseases in both genders. Circadian rhythm is
accountable for well-ordered roles of many different body functions. The
peak level of specific hormones and functions follow the biological
interpretations of circadian rhythm, whether daylight or night time.
Sleep disorders, aside from shift work, like obstructive sleep apnea,
can induce circadian disruption that influences complex immunological,
metabolic, and cardiovascular functions, eventually raising
cardiovascular diseases risk. Online databases were systematically
examined to investigate studies on randomized controlled trials (RCTs)
from the past five years, assessing the impact of varying sleep
disorders and shift work in inducing circadian disruption and its impact
on the risk of cardiovascular diseases. After administering multiple
inclusion and exclusion criteria, 18 studies were selected, but only
eight documents were chosen to review after a comprehensive analysis of
the studies. Each document was assessed for fitness of quality.
Sleep-related disorders and shift work were discovered to induce
circadian malfunction and disruption, and correlated with increased risk
of cardiovascular diseases. Approaches to control disorders of cause
should be developed to decrease the risk of cardiovascular
diseases.
Keywords: circadian disruption, insomnia, shift work,
cardiovascular risk, sleep