Results:
The baseline clinical data on age, sex, body mass index, smoking, left
ventricular ejection fraction, and so on are shown in Table 1. The
incidence of AKI was 27.5%.
According to the results of univariate analysis and clinical
significance, the following factors were included in the regression
analysis: age, hypertension, smoking, eGFR, LVEF, anaemia, proteinuria,
left main disease, ≥3 coronary artery lesions, ≥3 coronary anastomoses,
preoperative IABP implantation, blood transfusion, and ventilator time
(Table 2).
The results showed that eGFR, (OR=0.972, 95% CI=0.958-0.987, p< 0.001), ≥ 3 coronary anastomoses (OR=0.400, 95%
CI=0.230-0.693, p =0.001), preoperative IABP implantation
(OR=1.92, 95% CI=1.006-3.664, p =0.048) and ventilation time
(OR=1.016, 95% CI=1.007-1.026, p =0.001) were independent risk
factors for AKI. The results of multivariate regression analysis of
these risk factors are shown in Table 3. The area under the ROC curve
was 0.702, (95% CI [0.643-0.761], p < 0.001)
(Figure 1).
Postoperative complications indicated that 7 patients died in the AKI
group, which was significantly higher than the number of deaths in the
non-AKI group (7 (5.9%) vs 0 (0%) p < 0.001). In
addition, the rates of reoperation (10 (8.4%) vs 4 (1.3%)p =0.001) and postoperative myocardial infarction (34 (28.6) vs 26
(8.3%) p < 0.001), were higher in the AKI group than
in the non-AKI group. There was no significant difference in other
complications between the two groups, as shown in Table 4.