Results:
The baseline clinical data on age, sex, body mass index, smoking, left ventricular ejection fraction, and so on are shown in Table 1. The incidence of AKI was 27.5%.
According to the results of univariate analysis and clinical significance, the following factors were included in the regression analysis: age, hypertension, smoking, eGFR, LVEF, anaemia, proteinuria, left main disease, ≥3 coronary artery lesions, ≥3 coronary anastomoses, preoperative IABP implantation, blood transfusion, and ventilator time (Table 2).
The results showed that eGFR, (OR=0.972, 95% CI=0.958-0.987, p< 0.001), ≥ 3 coronary anastomoses (OR=0.400, 95% CI=0.230-0.693, p =0.001), preoperative IABP implantation (OR=1.92, 95% CI=1.006-3.664, p =0.048) and ventilation time (OR=1.016, 95% CI=1.007-1.026, p =0.001) were independent risk factors for AKI. The results of multivariate regression analysis of these risk factors are shown in Table 3. The area under the ROC curve was 0.702, (95% CI [0.643-0.761], p < 0.001) (Figure 1).
Postoperative complications indicated that 7 patients died in the AKI group, which was significantly higher than the number of deaths in the non-AKI group (7 (5.9%) vs 0 (0%) p < 0.001). In addition, the rates of reoperation (10 (8.4%) vs 4 (1.3%)p =0.001) and postoperative myocardial infarction (34 (28.6) vs 26 (8.3%) p < 0.001), were higher in the AKI group than in the non-AKI group. There was no significant difference in other complications between the two groups, as shown in Table 4.