Some reversibility
|
IV Pulse steroid
500 mg IV Methylprednisolone for 5 days
|
Right optic neuritis and aseptic neuritis
|
One dose
|
500 mg
|
IV
|
Female
|
30 years old
|
Our Case
|
Yes |
Cefotaxime 500 mg BID IV for one week |
Aseptic meningitis |
One
week |
400 mg BID |
Oral |
Male |
49 years old |
A.Viharika et al
[3] |
Yes |
Stopping Metronidazole |
Bilateral optic neuritis |
8 months |
400
mg BID |
Oral |
Female |
67 years old |
Nicole M McGrath et al
[4] |
No |
Stopping Metronidazole |
Bilateral optic neuritis and meylitis |
1
week |
1000 mg OD |
Oral |
Female |
57 years old |
Pai-Huei-Peng et al
[5] |
Yes |
Stopping Metronidazole |
Optic neuritis |
Two years |
NA |
NA |
Male |
36 years old |
Natalie Anwyll et al [6] |
Yes |
Stopping Metronidazole |
Aseptic meningitis |
One dose |
250 mg |
Oral |
Female |
20 years old |
Audrey P et al [7] |
Yes
|
Stopping Metronidazole
|
Optic neuropathy and cerebellar toxicity
|
For two years
|
500 mg
TID
|
oral
|
Female
|
58 years old
|
Erin Nuro et al [8]
|
Yes |
Stopping Metronidazole |
Bilateral optic neuritis |
Two weeks |
NA |
Oral |
Female |
6 years and 8 years old |
Bouraoui R et al
[9] |
Yes |
Stopping Metronidazole |
Aseptic meningitis |
One dose |
400 mg |
Oral |
Male |
42 years old |
Sujoy Khan et a [10] |
Some reversibility |
Stopping Metronidazole |
Optic neuritis |
7-365
days |
750-1000 mg daily |
Oral |
4 females and 3 males |
7 patients
from 26-53 years old |
Putnam et al [11] |
Yes
|
Stopping Metronidazole
Starting coenzyme Q10
|
Optic neuropathy and cerebellar toxicity
|
Over 6 months
|
500 mg TID
|
Oral
|
Male
|
17 years old
|
Kim M Cecil et al [12]
|
Yes |
Stopping Metronidazole |
Optic neuropathy |
2 years |
1500 mg
daily |
Oral |
Male |
20 years old |
De Bleecker et al
[13] |