Reversibility Treatment Outcome Duration Dose Route of administration Gender Age Case
Some reversibility
IV Pulse steroid 500 mg IV Methylprednisolone for 5 days
Right optic neuritis and aseptic neuritis
One dose
500 mg
IV
Female
30 years old
Our Case
Yes Cefotaxime 500 mg BID IV for one week Aseptic meningitis One week 400 mg BID Oral Male 49 years old A.Viharika et al [3]
Yes Stopping Metronidazole Bilateral optic neuritis 8 months 400 mg BID Oral Female 67 years old Nicole M McGrath et al [4]
No Stopping Metronidazole Bilateral optic neuritis and meylitis 1 week 1000 mg OD Oral Female 57 years old Pai-Huei-Peng et al [5]
Yes Stopping Metronidazole Optic neuritis Two years NA NA Male 36 years old Natalie Anwyll et al [6]
Yes Stopping Metronidazole Aseptic meningitis One dose 250 mg Oral Female 20 years old Audrey P et al [7]
Yes
Stopping Metronidazole
Optic neuropathy and cerebellar toxicity
For two years
500 mg TID
oral
Female
58 years old
Erin Nuro et al [8]
Yes Stopping Metronidazole Bilateral optic neuritis Two weeks NA Oral Female 6 years and 8 years old Bouraoui R et al [9]
Yes Stopping Metronidazole Aseptic meningitis One dose 400 mg Oral Male 42 years old Sujoy Khan et a [10]
Some reversibility Stopping Metronidazole Optic neuritis 7-365 days 750-1000 mg daily Oral 4 females and 3 males 7 patients from 26-53 years old Putnam et al [11]
Yes
Stopping Metronidazole Starting coenzyme Q10
Optic neuropathy and cerebellar toxicity
Over 6 months
500 mg TID
Oral
Male
17 years old
Kim M Cecil et al [12]
Yes Stopping Metronidazole Optic neuropathy 2 years 1500 mg daily Oral Male 20 years old De Bleecker et al [13]