Body weight and body composition
The change in body weight is summarized in Figure 1. The median weight
loss with a 95% confidence interval for the normal fasting glucose
group was 4.2 ± 1.3 kgs at 1 month and 10.1 ± 1.3 kgs at 3 months. The
total weight loss with a 95% confidence interval for the impaired
fasting glucose group was 4.5 ± 1.4 kgs at 1 month, 10.5 ± 1.3 kgs at 3
months. The IFG group had a statistically higher baseline weight than
the normal fasting glucose group patients. However, there was no
significant difference in the weight loss between the groups at any time
point. (fig 2)
The effect of the program on body fat composition is summarized in
Figure 2. The average mean estimated body fat percentage by BIA at
baseline was 41.5±0.9% for the IFG group and 40 ± .8% for the normal
fasting glucose group (p<0.05). However, there was no
significant difference in the reduction in percent fat between the above
two groups of patients over 12 weeks.
Fasting blood glucose
The average blood glucose level for the IFG group of patients at
baseline was 108.49 ± 6.4 mg/dl, with a statistically significant
decrease to 101.8 ±9.41 mg/dl (p<0.0001) at month 3. The
fasting blood glucose level for the group with normal fasting glucose at
entry was 89.8 ±6.61mg/dl with no clinically significant change at month
3 with fasting glucose levels of 91.1 ± 8.5 mg/dl.
By three months over 40% of the patients who lost 2.2-4.5 kg were able
to normalize their fasting blood glucose. Within the group of patients
able to lose more than 6.8 kg nearly 50% of patients normalized their
blood glucose. (Fig 3).