Body weight and body composition
The change in body weight is summarized in Figure 1. The median weight loss with a 95% confidence interval for the normal fasting glucose group was 4.2 ± 1.3 kgs at 1 month and 10.1 ± 1.3 kgs at 3 months. The total weight loss with a 95% confidence interval for the impaired fasting glucose group was 4.5 ± 1.4 kgs at 1 month, 10.5 ± 1.3 kgs at 3 months. The IFG group had a statistically higher baseline weight than the normal fasting glucose group patients. However, there was no significant difference in the weight loss between the groups at any time point. (fig 2)
The effect of the program on body fat composition is summarized in Figure 2. The average mean estimated body fat percentage by BIA at baseline was 41.5±0.9% for the IFG group and 40 ± .8% for the normal fasting glucose group (p<0.05). However, there was no significant difference in the reduction in percent fat between the above two groups of patients over 12 weeks.
Fasting blood glucose
The average blood glucose level for the IFG group of patients at baseline was 108.49 ± 6.4 mg/dl, with a statistically significant decrease to 101.8 ±9.41 mg/dl (p<0.0001) at month 3. The fasting blood glucose level for the group with normal fasting glucose at entry was 89.8 ±6.61mg/dl with no clinically significant change at month 3 with fasting glucose levels of 91.1 ± 8.5 mg/dl.
By three months over 40% of the patients who lost 2.2-4.5 kg were able to normalize their fasting blood glucose. Within the group of patients able to lose more than 6.8 kg nearly 50% of patients normalized their blood glucose. (Fig 3).