Effects of sevoflurane or propofol on CXCL12 and CXCR4
expressions
According to immunofluorescent staining, the intensity of C-X-C motif
chemokine ligand 12 (CXCL12) was increased in the sevoflurane group but
decreased in the propofol group (Fig 5A ). In similar, the
fluorescent staining of C-X-C motif chemokine receptor 4 (CXCR4) was
higher in the sevoflurane group than the control, and the intensity of
the marker was lower in the propofol group than the control (Fig
5B ). These results showed the expressions of CXCL12 and CXCR4 were both
increased by sevoflurane but decreased by propofol administration.