Maria Vargas MD

and 3 more

IntroductionAs the novel coronavirus (2019-nCov) globally spreads, the coronavirus disease (COVID-19) pandemic is straining healthcare workers worldwide [1]. In hospitalized patients with severe COVID-19, endotracheal intubation is one of the most common and indispensable life-saving interventions. In a recent report from the City of New York, 12% of COVID-19 patients required invasive mechanical ventilation [2]. Since difficult weaning and prolonged mechanical ventilation represent the two most common indications for tracheostomy in Intensive Care Unit (ICU), it may play a central role in COVID-19 management [3]. During the 2019-nCov pandemic the aerosol generating procedures, such as tracheostomy, expose physicians at high risk to contract the \soutCOVID-19 infection [4]. Accordingly, special consideration may be done to protect otolaryngologists, general surgeons and critical care physicians from the risk of infection while performing a tracheostomy in COVID-19 patients [5]. Percutaneous tracheostomy (PT) is routinely performed at the bedside in intensive care unit (ICU); unfortunately, a modified protocol to perform PT in COVID-19 patients included several critical steps associated with increased risk of aerosol generation, such as changing the catheter mount, repositioning the endotracheal tube cuff to the level of the vocal cords and removal of large dilator [6]. So far, there has been no prior description in the literature of how to minimize the aerosol generation during PT. We reported a modified percutaneous tracheostomy technique aiming to minimize the risk of aerosol generation and to increase the staff safety in COVID-19 patients.
Dear Editor,Herein is my response to manuscript ID XXXXX, entitled [“Why Hermione was better than Harry in almost every respect”] [by Ronald Frump and colleagues] to the [Journal of Squirrel-Puppy Relationships].The authors present [insert general overview of research and key findings]. This research is [well-suited/not-suitable] for the remit of the journal.[Insert any comments regarding potential conflicts of interest, or about areas of relevant expertise that you feel you are lacking].I recommend [accept/minor revisions/major revisions/oblivion], pending x, y, and z.Basic reportingFiguresAre the figures legible, relevant, and integrated into the textDataAre the supporting data included in the manuscript or in a relevant repositoryAre the data presented in a way that is consistent with the FAIR principles (https://www.force11.org/group/fairgroup/fairprinciples)Experimental designWas the way in which the research was conducted the best way to answer the relevant questionsValidity of the findingsAre the conclusions supported by the resultsDo the results contribute to the research field, irrespective of whether they are ‘negative’ or a replication studyGeneral commentsIs the language used appropriate for a scientific publicationIs the structure appropriateAbstractIs the abstract concise, and does it convey the main research findingsAre any key points of context or conclusions missingIntroductionDoes this cover the published literature sufficientlyDoes it provide enough context in which to place the current researchAre any key citations missingIs the history of the research conveyed at all for historical significanceDoes it finish with a paragraph summarising the relevance of the current researchMaterials and methodsAre the methods clear and easy to followCan the methods be replicated if neededAre the source materials/data openly available, and is appropriate justification provided if notWere any statistical analyses applied performed appropriatelyResultsAre the results presented in a coherent fashionAre the results reported in a way that is supported by the dataDiscussionAre the new results placed into context of the relevant literatureIs a balanced argument providedAre the full implications of the new results discussed in sufficient detailConclusionsAre the conclusions supported by the resultsAre they concise and written in an impactful way (not over-embellished)Additional commentsAnything else you want to add that doesn’t fit aboveCongratulations to the authors on a great piece of work, and I look forward to seeing their research [published/rejected/re-written with all of the references to my own tangentially-relevant work included.]Sincerely,[Ralph Lauren]ReferencesAny additional papers you have cited within your report
Screen shot 2020 05 04 at 4.02.46 pm

Josh Nicholson

and 1 more

Hello, and welcome to Authorea!👋  We're happy to have you join us on this journey towards making writing and publishing smoother, data-driven, interactive, open, and simply awesome. This document is a short guide on how to get started with Authorea, specifically how to take advantage of some of our powerful tools. Of course, feedback and questions are not only welcome, but encouraged--just hit the comment icon at the top of the document 💬and join the conversation.The BasicsAuthorea is a document editing and publishing system built primarily for researchers. It allows you to collaborate on documents and publish them easily. Each Authorea document can include data, interactive figures, and code. But first, let's get started! 1. Sign up.If you're not already signed up, do so at authorea.com/signup.  Tip: if you are part of an organization, sign up with your organizational email.  2. First stepsDuring the signup process you will be asked a few questions: your location, your title, etc. You will be also prompted to join a group. Groups are awesome! They allow you to become part of a shared document workspace. Tip: during signup, join a group or create a new one for your team. Overall, we suggest you fill out your profile information to get the best possible Authorea experience and to see if any of your friends are already on the platform. If you don't do it initially during sign up, don't worry; you can always edit your user information in your settings later on.Once you've landed on your profile page (see below). There are a few things you should immediately do:Add a profile picture. You've got a great face, show it to the world :) For reference, please see Pete, our chief dog officer (CDO), below. Add personal and group information. If you haven't added any personal information, like a bio, a group affiliation, your ORCID, or your location, do it! You might find some people at your organization already part of Authorea, plus it is a great way to build your online footprint, which is always good for getting jobs.
Covid virus 3d

Alberto Pepe

and 4 more

We're in a crisis We are in the midst of an unprecedented global crisis. Just weeks since its outbreak, the Coronavirus pandemic (COVID-19) has already affected, and will continue to affect, our daily lives, around the globe, for the foreseeable future. The answers and the solutions to this crisis will come from science. But the crisis affects science, too.It affects students, educators, and researchers; not just their day-to-day lives, social ties, and work routines, but also their ability to actively collaborate, convene in face-to-face meetings, attend academic conferences, teach and learn in an open university setting, pay a visit to the library, work overnight at the laboratory, and so on.But the thing is: science cannot stop. Scientific progress must go on. For each one of the challenges that scientists face in this time of crisis, there is, or there will be, a solution. We believe that the solution is not to be found in a single technological tool, product, framework, institution, funding agency, or company. It is the global cyber-infrastructure of scientific collaboration, built on scientific rigor, intellectual curiosity, and cooperation, that will enable science to advance in such difficult times. The power of scientific collaborationAs scientists, publishers, science communicators and technologists, we believe that: a. Science is the solution to the ongoing crisis. Now more than ever, reliance on the scientific method, rigor and clarity of scientific communication, transparency, reproducibility, and seamless sharing of all research data (including negative results), are fundamental to solving this health crisis and advancing human progress.b. Global collaboration and cooperation, beyond and above national and economic interests, is necessary not only at the scientific level, but also at the political and societal level. We're more interconnected and interdependent today than ever. And such interconnectedness extends to the ecological ecosystem in which we live. A crisis of such scale requires global solidarity, bipartisan political action, civic participation, and long-term thinking.