References
Anderson, D. E., & Johnstone, B. (2017). Dynamic Mechanical Compression of Chondrocytes for Tissue Engineering: A Critical Review. Front Bioeng Biotechnol, 5 , 76. doi:10.3389/fbioe.2017.00076
Butcher, D. T., Alliston, T., & Weaver, V. M. (2009). A tense situation: forcing tumour progression.Nature Reviews Cancer, 9 (2), 108-122. doi:10.1038/nrc2544
Caliari, S. R., & Burdick, J. A. (2016). A practical guide to hydrogels for cell culture. Nature methods, 13 (5), 405-414. doi:10.1038/nmeth.3839
Cambria, E., Brunner, S., Heusser, S., Fisch, P., Hitzl, W., Ferguson, S. J., & Wuertz-Kozak, K. (2020). Cell-Laden Agarose-Collagen Composite Hydrogels for Mechanotransduction Studies. Frontiers in Bioengineering and Biotechnology, 8 (346). doi:10.3389/fbioe.2020.00346
Cui, X., Hartanto, Y., & Zhang, H. (2017). Advances in multicellular spheroids formation. Journal of The Royal Society Interface, 14 (127), 20160877. doi:doi:10.1098/rsif.2016.0877
Davidenko, N., Hamaia, S., Bax, D. V., Malcor, J. D., Schuster, C. F., Gullberg, D., . . . Cameron, R. E. (2018). Selecting the correct cellular model for assessing of the biological response of collagen-based biomaterials. Acta Biomater, 65 , 88-101. doi:10.1016/j.actbio.2017.10.035
Davidenko, N., Schuster, C. F., Bax, D. V., Farndale, R. W., Hamaia, S., Best, S. M., & Cameron, R. E. (2016). Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry. J Mater Sci Mater Med, 27 (10), 148. doi:10.1007/s10856-016-5763-9
Fu, X. T., & Kim, S. M. (2010). Agarase: review of major sources, categories, purification method, enzyme characteristics and applications. Marine drugs, 8 (1), 200-218. doi:10.3390/md8010200
Gallo, L. C., Madaghiele, M., Salvatore, L., Barca, A., Scialla, S., Bettini, S., . . . Sannino, A. (2018). Integration of PLGA Microparticles in Collagen-Based Matrices: Tunable Scaffold Properties and Interaction Between Microparticles and Human Epithelial-Like Cells. International Journal of Polymeric Materials and Polymeric Biomaterials, 69 (3), 137-147. doi:10.1080/00914037.2018.1552857
Gallo, N., Lunetti, P., Bettini, S., Barca, A., Madaghiele, M., Valli, L., . . . Salvatore, L. (2020). Assessment of physico-chemical and biological properties of sericin-collagen substrates for PNS regeneration. International Journal of Polymeric Materials and Polymeric Biomaterials , 1-11. doi:10.1080/00914037.2020.1725755
Guimarães, C. F., Gasperini, L., Marques, A. P., & Reis, R. L. (2020). The stiffness of living tissues and its implications for tissue engineering. Nature Reviews Materials, 5 (5), 351-370. doi:10.1038/s41578-019-0169-1
Hamaia, S., & Farndale, R. W. (2014). Integrin Recognition Motifs in the Human Collagens. In D. Gullberg (Ed.), I Domain Integrins (Vol. 819, pp. 127-142).
Iglesias, M. J., Beloqui, I., Garcia-Garcia, F., Leis, O., Vazquez-Martin, A., Eguiara, A., . . . Martin, A. G. (2013). Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin. PloS one, 8 (10), e77281. doi:10.1371/journal.pone.0077281
Kruger, T. M., Bell, K. J., Lansakara, T. I., Tivanski, A. V., Doorn, J. A., & Stevens, L. L. (2019). Reduced Extracellular Matrix Stiffness Prompts SH-SY5Y Cell Softening and Actin Turnover To Selectively Increase Aβ(1–42) Endocytosis. ACS Chemical Neuroscience, 10 (3), 1284-1293. doi:10.1021/acschemneuro.8b00366
Li, Y., & Kumacheva, E. (2018). Hydrogel microenvironments for cancer spheroid growth and drug screening. Science Advances, 4 (4), eaas8998. doi:10.1126/sciadv.aas8998
López-Marcial, G. R., Zeng, A. Y., Osuna, C., Dennis, J., García, J. M., & O’Connell, G. D. (2018). Agarose-Based Hydrogels as Suitable Bioprinting Materials for Tissue Engineering. ACS Biomaterials Science & Engineering, 4 (10), 3610-3616. doi:10.1021/acsbiomaterials.8b00903
Malmqvist, M. (1978). Degradation of agarose gels and solutions by bacterial agarase. Carbohydrate Research, 62 (2), 337-348. doi:https://doi.org/10.1016/S0008-6215(00)80880-0
Monaco, G., Cholas, R., Salvatore, L., Madaghiele, M., & Sannino, A. (2017). Sterilization of collagen scaffolds designed for peripheral nerve regeneration: Effect on microstructure, degradation and cellular colonization. Mater Sci Eng C Mater Biol Appl, 71 , 335-344. doi:10.1016/j.msec.2016.10.030
Monteiro, M. V., Gaspar, V. M., Ferreira, L. P., & F., M. J. (2020). Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response. Biomater Sci
8 (7), 1855-1864. doi:10.1039/c9bm02075f
Napolitano, A. P., Dean, D. M., Man, A. J., Youssef, J., Ho, D. N., Rago, A. P., . . . Morgan, J. R. (2007). Scaffold-free three-dimensional cell culture utilizing micromolded nonadhesive hydrogels. Biotechniques, 43 (4), 494, 496-500. doi:10.2144/000112591
Nath, S., & Devi, G. R. (2016). Three-dimensional culture systems in cancer research: Focus on tumor spheroid model. Pharmacol Ther, 163 , 94-108. doi:10.1016/j.pharmthera.2016.03.013
Nguyen-Ngoc, K. V., Cheung, K. J., Brenot, A., Shamir, E. R., Gray, R. S., Hines, W. C., . . . Ewald, A. J. (2012). ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A, 109 (39), E2595-2604. doi:10.1073/pnas.1212834109
Oza, M. D., Prasad, K., & Siddhanta, A. K. (2012). One-pot synthesis of fluorescent polysaccharides: adenine grafted agarose and carrageenan. Carbohydrate Research, 357 , 23-31. doi:https://doi.org/10.1016/j.carres.2012.05.016
Petibois, C., Gouspillou, G., Wehbe, K., Delage, J. P., & Déléris, G. (2006). Analysis of type I and IV collagens by FT-IR spectroscopy and imaging for a molecular investigation of skeletal muscle connective tissue. Anal Bioanal Chem, 386 (7-8), 1961-1966. doi:10.1007/s00216-006-0828-0
Ranamukhaarachchi, S. K., Modi, R. N., Han, A., Velez, D. O., Kumar, A., Engler, A. J., & Fraley, S. I. (2019). Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis. Biomaterials Science, 7 (2), 618-633. doi:10.1039/c8bm01188e
Shin, S., Ikram, M., Subhan, F., Kang, H. Y., Lim, Y., Lee, R., . . . Yoon, S. (2016). Alginate–marine collagen–agarose composite hydrogels as matrices for biomimetic 3D cell spheroid formation. RSC Advances, 6 (52), 46952-46965. doi:10.1039/C6RA01937D
Singh, A., Brito, I., & Lammerding, J. (2018). Beyond Tissue Stiffness and Bioadhesivity: Advanced Biomaterials to Model Tumor Microenvironments and Drug Resistance.Trends in Cancer, 4 (4), 281-291. doi:10.1016/j.trecan.2018.01.008
Tang, Y., Liu, J., & Chen, Y. (2016). Agarose multi-wells for tumour spheroid formation and anti-cancer drug test. Microelectronic Engineering, 158 , 41-45. doi:https://doi.org/10.1016/j.mee.2016.03.009
Tasdemir, N., Bossart, E. A., Li, Z., & Zhu, L. (2018). Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures.78 (21), 6209-6222. doi:10.1158/0008-5472.can-18-1416
Teruki, N., Kimiko, M., & Yasuhiko, T. (2020). Three-Dimensional Culture System of Cancer Cells Combined with Biomaterials for Drug Screening. Cancers, 12 (10), 2754 (2751-2724). doi:https://doi.org/10.3390/cancers12102754
Terzi, A., Storelli, E., Bettini, S., Sibillano, T., Altamura, D., Salvatore, L., . . . Giannini, C. (2018). Effects of processing on structural, mechanical and biological properties of collagen-based substrates for regenerative medicine.Scientific Reports, 8 (1), 1429. doi:10.1038/s41598-018-19786-0
Tian, Z., Liu, W., & Li, G. (2016). The microstructure and stability of collagen hydrogel cross-linked by glutaraldehyde. Polymer Degradation and Stability, 130 , 264-270. doi:https://doi.org/10.1016/j.polymdegradstab.2016.06.015
Tibbitt, M. W., & Anseth, K. S. (2009). Hydrogels as extracellular matrix mimics for 3D cell culture.Biotechnology and Bioengineering, 103 (4), 655-663. doi:10.1002/bit.22361
Trappmann, B., Gautrot, J. E., Connelly, J. T., Strange, D. G. T., Li, Y., Oyen, M. L., . . . Huck, W. T. S. (2012). Extracellular-matrix tethering regulates stem-cell fate.Nature Materials, 11 (7), 642-649. doi:10.1038/nmat3339
Ulrich, T. A., Jain, A., Tanner, K., MacKay, J. L., & Kumar, S. (2010). Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices.Biomaterials, 31 (7), 1875-1884. doi:10.1016/j.biomaterials.2009.10.047
Vergara, D., Simeone, P., Franck, J., Trerotola, M., Giudetti, A., Capobianco, L., . . . Maffia, M. (2016). Translating epithelial mesenchymal transition markers into the clinic: Novel insights from proteomics. EuPA Open Proteomics, 10 , 31-41. doi:https://doi.org/10.1016/j.euprot.2016.01.003
Wang, Y., Gong, T., Zhang, Z. R., & Fu, Y. (2017). Matrix Stiffness Differentially Regulates Cellular Uptake Behavior of Nanoparticles in Two Breast Cancer Cell Lines. ACS Appl Mater Interfaces, 9 (31), 25915-25928. doi:10.1021/acsami.7b08751
Wong, S. H. M., Fang, C. M., Chuah, L. H., Leong, C. O., & Ngai, S. C. (2018). E-cadherin: Its dysregulation in carcinogenesis and clinical implications. Crit Rev Oncol Hematol, 121 , 11-22. doi:10.1016/j.critrevonc.2017.11.010