Chest tube outcomes with sirolimus use
Duration of chest tube after initiation of sirolimus ranged from 7- 20 days, with a mean of 16 days and median duration of 19 days. There were some interruptions in treatment due to infections, but no other sirolimus-related toxicity. The number of infections was considered similar to patients in NICU of same age and co-morbidities and not a side-effect of sirolimus. The medication was held during all episodes of proven or suspected infections and/or neutropenia.