2.3 Structural information
The sharing of infectious agent genomic data is critical against disease
outbreaks. Scientists are well awared to share the genomic and proteomic
data for better management of infectious diseases to develop
countermeasures. The SARS-CoV structural protein data was retrieved from
protein data bank (PDB) [13], I-TASSER (M=QHD4MOE) [14,15], and
SWISS-MODEL
(https://swissmodel.expasy.org/repository/species/2697049) (PDB
IDs: E=7k3g, N=6m3m, 6yun, S=7l09). The PDB (http://www.rcsb.org/pdb/)
is the single structural data archive of biological molecules. All the
data is primary, collected from depositors across the globe. The data of
macromolecules also contain the coordinates, structures and method of
structure determination. The I-TASSER and SWISS-MODEL servers have
already modelled the full-length proteins using NCBI reference data
(NC_045512) (GenBank MN908947). The SWISS-MODEL data are openly
accessible to everyone. The server also provides PDB experimental and
complex structural information of each SARS_CoV-2 protein. The I-TASSER
developed full-length COV-2 protein which is freely available to the
academic community (http://zhang.bioinformatics.ku.edu/I-TASSER).