Conclusion
Through the means of this literature review, we as the authors aspire to provide an effective
go – to article; a summary, of the clinical findings of VEXAS.
An increasing interest in adult-onset inflammatory conditions, in the recent years, have been noticed amongst rheumatologists. The innovative genotype first approach utilised in the discovery of VEXAS could be a motivation to incorporate similar study approaches to investigate other rheumatological conditions.
The authors encourage further funding, research and study into VEXAS. Further research into gene therapy is encouraged, which could potentially help to correct and adjust the somatic mutations described in this review article.