Data extraction
Two authors (LLS and IS) independently extracted data from the included studies using a predefined and structured data extraction form created for this systematic review. In addition to the outcomes of interest, we extracted the study characteristics (authors, year and journal of publication), study design, inclusion and exclusion criteria, number of patients and number of pregnancies with cirrhosis and if appropriate number of controls of all included studies. In case of studies missing data, we contacted first authors, at least two times, in attempt to request these data.