Design
Observational, prospective, longitudinal study on a tertiary PICU (14
bed with and a mean of 800 admissions per year). It was done in children
with asthma exacerbation and PICU admission (from October 2017 to
October 2019). The ethics committee from Hospital Infantil Universitario
Niño Jesús approved it. The data were obtained from clinical registers
and was performed following the principles of the Declaration of
Helsinki. The authors assume responsibility for the accuracy and
completeness of the data and analyses and for the fidelity of the
report. The attending in charge decided the clinical management based on
the clinical protocols applied in our unit. Children with severe
comorbidities or previous disease were excluded.