Patients
This 10-year prospective study (2010-2019) included children aged under
16 years who were referred to our allergy unit for an evaluation of BL
DHR.Reactions were classified as IR or NIR according to established
criteria5,10. For IRs, ST (prick tests and intradermal
tests) were carried out as recommended, with some
modifications19. For NIRs, we also followed the
pediatric adaptation5,8,21 of the 2004 general
recommendations made by the European Network for Drug Allergy (ENDA) and
the European Academy of Allergy and Clinical Immunology
(EAACI)20, that is, ST (delayed intradermal tests and
patch tests) followed by DPT when appropriate.