Introduction
Vaginitis is the most common infectious disease of female genital tract
during childbearing age. Common vaginal infections mainly include BV
(Bacterial Vaginosis), AV (Aerobic Vaginitis), VVC (Vulvovaginal
Candidiasis), and TV (Trichomoniasis)(1). Mixed vaginitis refers to the
infection of two or more pathogens in the vagina at the same time (2).
Common mixed vaginitis mainly includes BV+VVC, BV+AV, AV+VVC, TV+AV,
TV+BV, TV+VVC, etc. Existing studies have shown that the prevalence of
mixed infections during pregnancy is 6.5%-13.2%(3-5), which is higher
than that of 2.4%-6.4% in non-pregnant women(6, 7).Low income, low
education level, previous vaginal infections, poor personal hygiene,
history of antibiotic use, and external hemorrhoids are known risk
factors for BV, VVC and AV during pregnancy, but no studies have
analyzed the risk factors of pregnant women with mixed vaginitis(5, 8).
It is known that single vaginitis during pregnancy, such as AV, BV, and
VVC, is associated with the increase in the incidence of PROM (premature
rupture of membranes), premature delivery, etc(1, 5). The effect of
mixed vaginitis on pregnancy outcome still needs further research.
Whether the symptoms, signs and laboratory features of women with mixed
vaginitis during late pregnancy are also confused with single vaginitis
remains to be studied. Therefore, this study analyzed the mixed
vaginitis in late pregnancy to summarize the epidemiological
characteristics, risk factors, clinical symptoms and signs, laboratory
characteristics, and their impact on adverse pregnancy outcomes in women
with mixed vaginitis in the third trimester, so as to provide
suggestions for clinical diagnosis and treatment.