Conclusion
Due to reduced immunity and increased disease susceptibility, mixed
vaginitis is prone to occur during pregnancy. A positive glucose
tolerance test during pregnancy and a history of vaginitis during
pregnancy are risk factors for mixed vaginitis in late pregnancy. The
symptoms and signs of women with mixed vaginitis during pregnancy are
difficult to distinguish from women with simple vaginitis and are
related to the adverse outcome of puerperal infection. It is recommended
to efficiently distinguish mixed vaginitis through laboratory
examination. Therefore, vaginitis should be diagnosed and treated during
early pregnancy, and blood glucose management should be guided in time
during pregnancy to prevent puerperal infection.
Conflicts of Interest: The authors declare no conflict of interest.
Financial disclosure: The authors declare no financial disclosures.
Author’ Contributions: All authors fulfilled the conditions required for
authorship and have approved this submission. HL, CH, and FX conceived
the study question, and all authors were involved in the study design.
HL, and YY were involved in the statistical analysis while HL, MD,and WX
interpreted the results. HL created the first draft of the manuscript.
MD, WX, WQ, FT, HL, and CW made substantial contributions to drafting
the article and revising it critically. Furthermore, all authors have
given their final approval for this version to be published and agree to
be accountable for all aspects of the work.
Acknowledgements: Not applicable.
Ethics approval:This project was approved by the Ethics Committee of
Tianjin Medical University General Hospital. (Ethical NO.
IRB2020-WZ-194, 15 December 2020)
Funding: This work was supported by Tianjin Municipal Science and
Technology Commission Special Foundation for Science and Technology
Major Projects in Control and Prevention of Major Diseases (Grant No.
18ZXDBSY00200), General Project of the National Natural Science
Foundation of China (Grant No. 82071674) and Tianjin Health Science and
Technology Project (Grant No. KJ20003).
Supporting Information:Additional supporting information may be found
online in the Supporting Information section at the end of the article.
Table 1. Comparison socio-demographic characteristics of mixed vaginitis
with single vaginitis during pregnancy.
Table 2. Risk factors associated with mixed vaginitis during pregnancy.
Table 3. Comparison clinical symptoms and signs and laboratory
characteristics of mixed vaginitis with single vaginitis during
pregnancy.
Table 4. Comparison pregnancy outcomes of mixed vaginitis with single
vaginitis.
Table S1. Prevalence of single and mixed vaginitis in pregnancy peoples.