Author contributions
L.T. and V.E. designed the experiments, analysed the data, supervised
the study and wrote the manuscript; C.A., A.P., R.P. and A.D.S performed
in vitro studies on NETs release, DNA measurement and confocal
microscopy; G.D. performed biochemical studies and western blot
analysis; N.M. performed flow cytometry; R.P. performed cytokine
measurements; A.R., S.R., I.D.F. and A.B. conducted in vivoexperiments; P.M. recruited patients; M.R. and A.B. wrote the
manuscript.