METHODS
Subjects :
The study protocol was approved by the Local Ethics Committee of Faculty
of Medicine, University of Alexandria (0201018) that is conformed to the
ICH GCP guidelines. All participants provided a written informed consent
to inclusion of the clinical and laboratory data for research purposes
upon fulfilling the study enrollment criteria.
Thirty MS cases, who presented to the MS Clinic of Alexandria University
Hospital, were enrolled in our study. These were diagnosed clinically
according to revised McDonald criteria 2017. (11) In
addition, complete neurological and systemic examination including
expanded disability status scale (EDSS). (12)
A cross matching control group of twenty healthy subjects of similar age
and sex were included.