4. Conclusions
The Tm and Ts of the studied lipid
mixtures were affected by the pressure; they decreased with increasing
pressure up to a pressure of 150 bar and then began to increase linearly
with the increase in pressure. Based on Tm behavior, it
was observed that the temperature of 60 ° C ensures that both pure
beeswax and mixtures of beeswax with edible oils are melted at pressures
equal to or greater than 50 bar, however, to ensure that the CO2 present
in the medium is in the supercritical state, pressures greater than 75
bar are recommended, which indicates that these materials are potential
carriers for lipid particles loaded with bioactive compounds formed by
supercritical precipitation using CO2 as a solvent.
The higher the pressure applied in the process, the higher the
solubility of the CO2 in lipid mixtures and the greater
the volumetric expansion observed, in the studied pressure range.
These results could be used, as a preliminary study, for the design of
lipid particles loaded with bioactive compounds by supercritical
CO2 technology employing at moderate temperature to be
used in the formulation of innovative and functional food and
pharmacological products.