Management of ARDS related to COVID-19
1. Ventilation settings were adjusted, considering physiologic changes
of pregnancy. The SpO2 was maintained ≥ 94%(12). The
goal for PaO2 was > 70mmHg and for
PaCO2 < 50mmHg(12). In most cases, the
decision for proning was made if the P/F ratio was < 150 on ≥
60% FiO2 and ≥ 10 of PEEP(7). This should serve as a
general rule for initiating and discontinuing proning sessions.
2. The principles of medical treatment are highlighted below and
summarized in supplemental Catalog 1. Coverage for superimposed
pneumonia was typically provided for patients that required increasing
respiratory support. Remdesivir, Canakinumab, Tocilizumab, and
convalescent plasma were offered based on inclusion criteria for
treatment or clinical trial. Antenatal corticosteroids were administered
between 24 and 34 weeks if there was a concern for imminent delivery.