Statistics
Statistical analysis was performed in Prism 8 (GraphPad). Differences
between multiple groups was determined via one-way ANOVA with Dunnett
post-test comparing all treatment groups to PEI treatment. Differences
between two groups was calculated using Student’s t test.
Significance designated: *p < 0.05, **p < 0.01, ***p
< 0.001, ****p < 0.0001.