Markers of mineral metabolism
Changes in markers of mineral metabolism are presented in Table 2. The
average serum phosphate level was within normal range for both treatment
groups, 3.7 ± 0.73 and 3.3 ± 0.70 for CA and SC, respectively. In both
treatments, within groups the levels of phosphate and calcium remained
clinically unchanged. Sevelamer treatment resulted in a significant
decrease in levels of FGF-23, calcidiol, and calcitriol, whereas FGF-23
and calcitriol remained unchanged in the calcium acetate group. A
significant increase in calcidiol, was observed in the calcium acetate
group. PTH decreased significantly in the calcium acetate group but not
in the sevelamer carbonate group.