Markers of mineral metabolism
Changes in markers of mineral metabolism are presented in Table 2. The average serum phosphate level was within normal range for both treatment groups, 3.7 ± 0.73 and 3.3 ± 0.70 for CA and SC, respectively. In both treatments, within groups the levels of phosphate and calcium remained clinically unchanged. Sevelamer treatment resulted in a significant decrease in levels of FGF-23, calcidiol, and calcitriol, whereas FGF-23 and calcitriol remained unchanged in the calcium acetate group. A significant increase in calcidiol, was observed in the calcium acetate group. PTH decreased significantly in the calcium acetate group but not in the sevelamer carbonate group.