Cl=confidence interval; OR=oddsratio; CAD, Coronary artery disease; CAR, C-reactive protein to albumin ratio; eGFR, estimated glomerular filtration rate; IRA, Infarct releated artery

In the ROC analysis performed to predict TIMI flow 0-1, the optimal predictive value for CAR was 0.375 with 48% sensitivity and 84% specificity. The ROC curves were compared to evaluate whether CAR has additional distinctive value on the CRP and albumin levels. CAR’s Area Under Curve (AUC) value was statistically significantly higher compared to CRP (AUC: 0.59; 95%CI: 0.55-0.63, p=0.014) and albumin (AUC: 0.57; 95%CI: 0.53-0.62, p=0.028) in predicting TIMI flow 0-1 (Figure 1).

Figure 1. The receiver operating characteristic (ROC) curve comparison of C-reactive protein (CRP), albumin, and C-reactive protein to albumin ratio (CAR) in the prediction of baseline IRA patency