Abstract
Lentigines are brown macules which develop due to increased
proliferation of melanocytes at the dermo-epidermal junction. We report
three cases of acral lentiginosis in children following chemotherapy for
acute lymphoblastic leukaemia (ALL) which have persisted following
cessation of chemotherapy, despite avid photoprotection. Generalised
eruptive naevi with subsequent development of dysplastic naevi and
melanoma in situ have been reported following chemotherapy, highlighting
the importance of continued clinical observation.