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A large right atrial thrombus penetrating through a patent foramen ovale in a patient with Prothrombin G2120 Mutation
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  • Ricardo Patricio Pérez Anderson,
  • Johannes Boehm,
  • Ruediger Lange,
  • Ralf Guenzinger
Ricardo Patricio Pérez Anderson
German Heart Centre Munich

Corresponding Author:[email protected]

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Johannes Boehm
German Heart Center Munich
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Ruediger Lange
German Heart Center Munich
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Ralf Guenzinger
German Heart Center Munich
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Abstract

Abstract: The Prothrombin mutation G2021 alone is considered a minor risk factor for thromboembolism, but thromboembolic events are more likely in the presence of additional risk factors. We report on a 44-year-old female with an atrial thrombus causing pulmonary embolism and transiting through a patent foramen ovale. The thrombus was extracted by open heart operation. The patient had a family history for thromboembolic events. Further diagnostic after surgery found the patient positive for the Prothrombin mutation G2021, but not for the Factor V Leiden mutation. After surgery, a permanent oral anticoagulation has been started.