Clinical manifestations of different aPLs in APS patients
Correlations between different aPLs and LA or clinical manifestations
were shown with odds ratios in table 3. Presence of LA was significantly
associated with IgG of aCL (ORs 9.0, 95% CI 2.6-31.0), aβ2GPI (ORs
14.1, 95% CI 1.9-107.2), aPS/PT (ORs 4.7, 95% CI 1.1-21.2), and aAnxV
(ORs 21.5, 95% CI 2.8-163.0). Among all microangiopathy manifestations,
stroke was significantly associated with aβ2GPI IgG (ORs 4.7, 95% CI
1.2–18.5) as well as aPS/PT IgG (ORs 6.5, 95% CI 1.6-25.9).
Additionally, aPS/PT IgM was reversely associated with pregnancy loss in
women (ORs 0.6, 95% CI 0.5-0.7).