APS (151) APS (151) APS (151) SLE (71) SLE (71) Health controls (90)
Primary (100) Primary (100) Secondary (51)
Gender (female/male) 63/37 45/6 45/6 61/10 41/49 41/49
Mean age (years ± SD) 36.3±12.1 32.9±10.2 32.9±10.2 30.1±8.2 43.4±12.2 43.4±12.2
Clinical manifestations
Thrombosis, n (%) 80(80.0%) 38(74.5%) 38(74.5%) 0 NA NA
Pregnancy morbidity, n (%) 33(33.0%) 16(31.4%) 16(31.4%) 0 NA NA
Thrombosis + pregnancy morbidity, n (%) 13(13%) 3(5.9%) 3(5.9%) 0 NA NA
LA, n (%) 73(73.0%) 44(86.3%) 44(86.3%) 17(23.9%) NA NA
History of arterial thrombosis, n (%) 43(43.0%) 21(41.2%) 21(41.2%) 0 NA NA
Stroke, n (%) 4(4.0%) 2(3.9%) 2(3.9%) 0 NA NA
Coronary heart disease, n (%) 9(9.0%) 2(3.8%) 2(3.8%) 0 NA NA
Eye involvement, n(%) 3(3.0%) 1(2.0%) 1(2.0%)
Lower limb artery occlusion, n (%) 1(1.0%) 0 0 0 NA NA
History of venous thrombosis, n (%) 47(47.0%) 24(47.1%) 24(47.1%) 0 NA NA
Deep vein thrombosis, n (%) 19(19.0%) 7(13.7%) 7(13.7%) 0 NA NA
Pulmonary embolism, n (%) 19(19.0%) 2(3.9%) 2(3.9%) 0 NA NA
Upper limb vein thrombosis, n (%) 0 1(2.0%) 1(2.0%) 0 NA NA
Renal vein thrombosis, n (%) 1(1.0%) 0 0 0 NA NA
Portal vein thrombosis, n (%) 4(4.0%) 1(2.0%) 1(2.0%) 0 NA NA
Cerebral venous and sinus thrombosis, n (%) 3(3.0%) 1(2.0%) 1(2.0%) 0 NA NA
Central retinal venous occlusion, n (%) 1(1.0%) 0 0 0 NA NA
Microangiopathy, n (%) 57(57%) 24(47.1%) 24(47.1%) 0 NA NA
TP, n (%) 38(38%) *28(54.9%) *28(54.9%) 21(29.6%) NA NA
Heat valve disease, n (%) 0 6(11.8%) 6(11.8%) 0 NA NA
Non-stroke CNS manifestations, n (%) 4(4.0%) 4(7.8%) 4(7.8%) 0 NA NA
Antiphospholipid syndrome nephropathy, n (%) 6(6.0%) 2(3.8%) 2(3.8%) 0 NA NA
Autoimmune hemolytic anemia, n (%) 1(1.0%) 5(9.8%) 5(9.8%) 0 NA NA
Thrombotic Microangiopathy, n (%) 0 1(2.0%) 1(2.0%) 0 NA NA
Hemolytic uremic syndrome, n (%) 1(1.0%) 0 0 0 NA NA
History of adverse pregnancy, n (%) 37(37%) 20(39.2%) 20(39.2%) 4(5.6%) NA NA
Early fetal loss (<10 weeks), n (%) 12(12.0%) 8(15.7%) 8(15.7%) 4(5.6%) NA NA
Late fetal loss (10-28 weeks), n (%) 19(19.0%) 12(23.5%) 12(23.5%) 0 NA NA
Placental insufficiency, n (%) 14(14.0%) 7(13.7%) 7(13.7%) 0 NA NA