Results:
The frequency of clinically significant hypoglycaemia (blood glucose
< 3 mmol/L) during the 4 week period of SMBG was 38.8%, while
the frequency of severe hypoglycaemia over the last one year was 22.5%.
Based on the Gold score and Clarke score, 28.3% and 24.6% of subjects
respectively had IAH. The Clarke score was associated with increased
frequency of clinically significant hypoglycaemia, severe hypoglycaemia
and hospitalizations for hypoglycaemia. Prior group education, education
from a dietitian and education on blood glucose targets were associated
with lower Clarke scores, while adjusting insulin doses for blood
glucose using an insulin sensitivity factor was associated with lower
Gold and Clarke scores.