Author Contributions:
KS, MH, MI prepared the manuscript and figures
, and the data were analyzed and interpreted by KS, FI, AT, YM, and TO; MT, TI, MMU, and TT reviewed the manuscript; and KS, MM, and YO revised the manuscript for important intellectual content. All authors have read and approved the final version of this manuscript.
Acknowledgments: The authors thank Editage for English language editing (https://www.editage.com/).