5. Conclusion
In summary, our findings suggest that high levels of adipose tissue in
CT parameters including TATI, VATI, and SATI may be a possible predictor
of OS in patients with mRCC treated with targeted therapy, and also SMI
may be a predictor for PFS. Considering the widely disparate results of
the studies, the prognostic value of body composition (BMI, SATI, VATI,
SMI) and their alterations in the course of mRCC should be evaluated in
a larger patient population with prospective design to validate cut-off
values for these parameters. If our results are corroborated by future
trials, the measurement of VBC parameters and incorporation of those
into the current scoring systems would provide better prognostication
and personalized treatment in mRCC.