2. Optical biosensors for detection of Brucella spp
Optical biosensors have extensively been applied for the identification
of infectious bacteria because of their sensitivity, rapid response, and
adaptability with different assay conditions
(Singh, Poshtiban, & Evoy, 2013).
Optical biosensors comprise of a light source, as well as various
optical segments to produce a light bar
with explicit attributes and a
modified sensing head along with a photodetector to beeline this light
to a modulating agent (Mehrotra, 2016).
Optical biosensors are classified into subcategories of
surface
plasmon resonance (SPR), colorimetric, fluorescence, and
chemiluminescence sensors
(Rubab et al., 2018). Among these,
colorimetric sensors make it possible to detect the causative agent
in
an easier and quicker manner while they are also portable and
cost-effective. The attractive colorimetric method allows rapid
recognition of pathogens by a color change in the sample in about 15
min. Response signals can be seen with the naked eye without
pre-enrichment steps (Rubab et al.,
2018).