2. Optical biosensors for detection of Brucella spp
Optical biosensors have extensively been applied for the identification of infectious bacteria because of their sensitivity, rapid response, and adaptability with different assay conditions (Singh, Poshtiban, & Evoy, 2013). Optical biosensors comprise of a light source, as well as various optical segments to produce a light bar with explicit attributes and a modified sensing head along with a photodetector to beeline this light to a modulating agent (Mehrotra, 2016).
Optical biosensors are classified into subcategories of surface plasmon resonance (SPR), colorimetric, fluorescence, and chemiluminescence sensors (Rubab et al., 2018). Among these, colorimetric sensors make it possible to detect the causative agent in an easier and quicker manner while they are also portable and cost-effective. The attractive colorimetric method allows rapid recognition of pathogens by a color change in the sample in about 15 min. Response signals can be seen with the naked eye without pre-enrichment steps (Rubab et al., 2018).