3.3. Zinc oxide nanoparticles (ZnO-NPs) sensors for diagnosis ofBrucella
ZnO NPs are new type of cheap and low-toxicity nanomaterials which have
several therapeutic applications against cancers, microbial infections,
inflammations, diabetes, as well as
usage in bioimaging and drug delivery
(Wahab, Khan, Ahmad, Musarrat, &
Al-Khedhairy, 2017). Wahab et al. developed a ZnO-NPs based sensor for
the identification of Brucella. They tried to design an
affordable and low-cost biosensor to detect Brucella in milk
samples to be used by rural people. To do this, the anti-Brucellaantibody was functionalized on ZnO-NPs and the resulted NPs were
deposited on aluminum sheets (Al-sheet). The developed Al-sheets were
then used as electrode components for voltametric detection (CV) of the
bacterium (Wahab et al., 2017). The
detection scheme is shown in figure 5.