3.3. Zinc oxide nanoparticles (ZnO-NPs) sensors for diagnosis ofBrucella
ZnO NPs are new type of cheap and low-toxicity nanomaterials which have several therapeutic applications against cancers, microbial infections, inflammations, diabetes, as well as usage in bioimaging and drug delivery (Wahab, Khan, Ahmad, Musarrat, & Al-Khedhairy, 2017). Wahab et al. developed a ZnO-NPs based sensor for the identification of Brucella. They tried to design an affordable and low-cost biosensor to detect Brucella in milk samples to be used by rural people. To do this, the anti-Brucellaantibody was functionalized on ZnO-NPs and the resulted NPs were deposited on aluminum sheets (Al-sheet). The developed Al-sheets were then used as electrode components for voltametric detection (CV) of the bacterium (Wahab et al., 2017). The detection scheme is shown in figure 5.