Demographic Characteristics Associated with Increased Incidence of Suicide and Accidental Death
There were 27 suicides and 77 accidental deaths among patients with ovarian cancer who were younger than 50 years old. These younger cancer patients had almost the same risk of suicide as the general population with the same distribution of age, sex, and race (SMR=1.25; 95% CI [0.86-1.83]). But a significantly higher incidence of suicide and accidental death in patients over 50 were observed. Among cancer patients diagnosed between 50 and 59 years old, there were 36 suicides of 32,298 patients, accounting for 33.6% of all suicides among patients with ovarian cancer (Supplementary Table.1) . While for patients whose age at diagnosis was more than 50 years old, the suicide risk gradually decreased with age but increased after the age of 80.Supplementary Figure.3 showed the number and proportion of suicides and accidental deaths in patients with ovarian cancer of different histological subtypes at different ages.
Among all patients with ovarian cancer, white patients had the highest risk of suicide (SMR=1.82; 95% CI [1.50-2.23]) and black patients had the highest risk of accidental death (SMR=1.87; 95% CI [1.27-2.75]). The predominant patients who committed suicide were those with high education level (42, 39%), high income (43, 40%), and metropolitan residents (97, 91%), with an SMR of 2.12 (95% CI [1.57-2.87]), 2.05 (95% CI [1.52-2.77]), and 1.93 (95% CI [1.58-2.35]), respectively.