Multivariate analysis
The results of the logistic regression analysis for in-hospital
mortality events are presented in Table 3. Male sex (odds ratio
[OR]: 1.71, 95% confidence interval [CI]: 1.07–2.75, p =
0.026]), CHF (OR: 1.79, 95% CI: 1.04–3.07, p = 0.034), history of
malignancy (OR: 2.46, 95% CI: 1.24–4.24, p = 0.0012), lower albumin
level (OR: 0.35, 95% CI: 0.24–0.53, p < 0.001), higher BUN
level (OR: 1.02, 95% CI: 1.01–1.04, p < 0.001), higher
A-DROP score (OR: 1.76, 95% CI: 1.4–2.21, p < 0.001), lower
GNRI (OR: 0.94, 95% CI: 0.92–0.95, p < 0.001), and initial
antibiotic change (OR: 4.32, 95% CI: 2.69–6.95, p < 0.001)
were identified as significant prognostic factors in the univariate
analysis. Male sex (OR: 1.88, 95% CI: 1.07–3.31, p = 0.028), CHF (OR:
2.14, 95% CI: 1.11–4.12, p = 0.023), history of malignancy (OR: 2.66,
95% CI: 1.41–5, p = 0.0025), higher A-DROP score (OR: 1.48, 95% CI:
1.16–1.9, p =0.002), lower GNRI (OR: 0.91, 95% CI: 0.87 to 0.95,
P<0.001), and an initial antibiotic change (OR: 4.22, 95% CI:
2.48–7.19, p < 0.001) were identified as independent adverse
prognostic factors in the multivariate analysis.