Figure 1. The expression of miR-143-3p in peripheral blood CD4+T cells of RA patients and its correlation with DAS28 and ESR levels.
(A-C) The correlation between DAS28 and ESR (n=31, r=0.6681, P=0.0001) and CRP (n=31, r=0.3623, P=0.0226) and IgG levels (n=31, r=0.3568, P=0.0244). The Pearson correlation coefficient was determined.
(D) Quantification of miR-143-3p mRNA in peripheral blood CD4+T cells of moderate RA patients (n=13) and moderate RA patients (n=18) and healthy controls (n=24). Data were expressed as the mean ± SEM. * p < 0.05, **p < 0.01, by one-way ANOVA with Dunnett’s post-hoc test.
(E-F) The correlation between miR-143-3p expression and DAS28 (n=31, r=-0.5534, ***, P=0.0006) and ESR levels (n=31, r=-0.3422, *, P=0.0297). The Pearson correlation coefficient was determined.