Figure 8. Induction of miR-143-3p overexpression facilitates Treg differentiation in CIA mice.
(A) Representative dot plots of CD4+CD25+Foxp3+cells in blood and spleen of miR-143-3p-treated CIA mice.
(B) CD4+CD25+Foxp3+cells in blood and spleen of miR-143-3p-treated CIA mice.
(C) The levels of IL-10 in the plasma of miR-143-3p-treated CIA mice.
(D) The mRNA expression of Foxp3 in the splenic and lymphatic CD4+T cells of miR-143-3p-treated CIA mice.
Data were expressed as the mean ± SEM (n=6). * p < 0.05, **p < 0.01 compared with the control group by Student’s t test.