Phenotype of infants with intact CAR during assessment (group1):
Figure 3-A1 is a graphical representation of the FiO2, SpO2 and HR trends during CAR assessment test in one of the cases from group 1 . During stepwise reduction of FiO2 from 0.57 to 0.38, the SpO2 was maintained (figure 3-A2). A self-resolved hypoxemic episode resulted in cessation of the test at 12 minutes. Figure 3-a (B) shows that despite SpO2 fluctuation, crRTO was maintained linearly; but FOE was concordant linearly with SpO2. Table 3 shows the poor positive correlation of SpO2 with crRTO and with FiO2, and poor negative correlation of SpO2 with HR(r <0.5). The correlation between SpO2and FOE was strong in infants of this group (r >0.5), and there was a poor correlation between SpO2 and crRTO during the significant hypoxemic episode.