Experimental design and statistical analysis
All experiments with at least three biological replications were
analyzed by Graphpad Prisim 9.0 statistical software using one-way or
two-way analysis of variance (ANOVA). The values presented were the
means ± one standard deviation (SD) of three biological replicates.P values were corrected with Bonferroni,* P <
0.05, ** P < 0.01, *** P < 0.001, ****P < 0.0001.