3.7 Risk factors for patients with multiple FOB therapy
Univariate analysis identified peak body temperature, duration of fever
and hospitalization, hypoxemia, complications of extrapulmonary,
presence of pleural effusion, higher level of inflammation indicators
and D-dimer as significant related factors for multiple FOB. ROC
analysis revealed that N%, LDH and D-dimer were of great significance
in identifiying subjects required multiple FOB. The cutoff values for
these three variables were 75.5%, 598.5U/L and 0.45mg/L with maximum
sensitivities and specificities. To adjust for the influence of
confounders, multivariate logistic regression analysis was performed,
and results showed that N%, LDH and D-dimer were independent risk
factors for multiple FOB with the odds ratio (OR) values of 3.777, 2.729
and 2.272, respectively. (Table 6)