3.7 Risk factors for patients with multiple FOB therapy
Univariate analysis identified peak body temperature, duration of fever and hospitalization, hypoxemia, complications of extrapulmonary, presence of pleural effusion, higher level of inflammation indicators and D-dimer as significant related factors for multiple FOB. ROC analysis revealed that N%, LDH and D-dimer were of great significance in identifiying subjects required multiple FOB. The cutoff values for these three variables were 75.5%, 598.5U/L and 0.45mg/L with maximum sensitivities and specificities. To adjust for the influence of confounders, multivariate logistic regression analysis was performed, and results showed that N%, LDH and D-dimer were independent risk factors for multiple FOB with the odds ratio (OR) values of 3.777, 2.729 and 2.272, respectively. (Table 6)